Everybody has their own way of doing things. So here is mine gleaned from multiple hot weather (90's to 102F) trips to the mountains here.
The round trip is between 59 and 73 miles depending on what destination is chosen (50% freeway, 30% highway, 20% winding mountain "highway"). With elevation changes of 2900 ft up to 5600 ft, depending on what destination is chosen. After experimenting, I have found the most comfort and (perceived) least power consumption for running the AC with the temperature control set at the coldest setting and varying the fan speed in the lower ranges to maintain comfort.
The biggest adjustment for me was paying more attention to the temp in the car. With an ICE, I often would not cut back the AC until a chill brought it to my attention. In an EV this would be very wasteful. I mostly drive with the temperature comfortable not just "tolerable". Often while up in the mountains the AC button can be pushed to turn the compressor function off, leaving the fan on low or mid setting to continue to pull the cool out of the evaporator coil until the air warms enough to push the AC back on for a while. I find this to be much more comfortable and use less power overall than running a bunch of airflow at a warmer temperature control setting. Humidity is generally lower here than some places which allows the AC to work more efficiently at cooling the interior, than if the humidity was really high. Recirculate setting of course, so you are Re cooling, cooler, already dried air, instead of warmer, moister outside air.
Colder air coming from the vents more slowly does a better job of making most people comfortable with the least energy used. Similarly, a radiant heater placed near individuals will make them feel comfortable using far less energy than raising the air temperature of the entire room to a comfortable level. I figure, why cool the back seat too when there is nobody back there?
Pretty impressive (to me) that this little wonder of a car can consistently make these trips (over 5000 ft of climbing!!) and keep us comfortable with a "comfortable" range margin too.
Aerowhatt